In another tragic turn of events, Joe lost Beau to a years-long battle with brain cancer in 2015. According to the New York Times, Beau's dying wish was to see his father run for President in 2016. "When Beau realized he was not going to make it, he asked his father if he had a minute to sit down and talk …," Times columnist Maureen Dowd wrote. "Beau was losing his nouns and the right side of his face was partially paralyzed. But he had a mission: He tried to make his father promise to run, arguing that the White House should not revert to the Clintons and that the country would be better off with Biden values."
Biden, of course, chose not to run. "Unfortunately, I believe we're out of time, the time necessary to mount a winning campaign for the nomination," Biden said, according to the Times. "But while I will not be a candidate, I will not be silent." According to CNN, Biden said his decision not to run left him with daily regret, but that "it was the right decision for my family and for me."