During the 2006 Nickelodeon special "Behind the Clues: 10 Years with Blue," Steve Burns said he realized he was losing his hair quickly at age 29. It became the main reason why he left "Blue's Clues."

After "Blue's Clues," Burns made a splash as a musician, and in 2003, Burns released his first album, "Songs for Dustmites." One of the album's tracks, "Mighty Little Man," was used as the theme song of the CBS sitcom "Young Sheldon."

"Blue's Clues" went off the air in 2006, but returned as the Nickelodeon revival series "Blue's Clues & You!" starring Josh Dela Cruz, in 2019. In the premiere, Burns appeared along with on-screen brother Joe (Donovan Patton).

To celebrate the show's 25th anniversary in September, Burns filmed a video discussing the in-universe reason why Steve left the show. “I just kinda got up and went to college," he said, adding, "That was really challenging, by the way, but great because I got to use my mind and take a step away.”